Supplementary Figure S5 from T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma

Key Points

• T-cell dependency plays a crucial role in tumor regression in preclinical models of pancreatic cancer.
• Inhibition of RAS(ON) significantly alters the PDAC tumor immune microenvironment.
• The study utilized preclinical models to assess the impact of RAS(ON) on tumor dynamics.
• Understanding T-cell interactions may enhance cancer treatment strategies for pancreatic ductal adenocarcinoma.

Abstract