Use of medications with pharmacogenomic guidelines and adverse outcomes in hospitalised older patients: a retrospective cross-sectional study

Key Points

• Adverse outcomes are significantly associated with medications not guided by pharmacogenomic guidelines, highlighting risks.
• In the analysis, 75% of adverse outcomes occurred in cases where pharmacogenomic guidelines were overlooked.
• Retrospective cross-sectional analysis compared prescriptions to pharmacogenomic guidelines among older hospitalized patients.
• Findings emphasize the need for integrating pharmacogenomic guidelines to lessen medication-related risks in older adults.