Importance of changes in body mass index from adolescence to middle age as a risk factor for osteoporosis: the Japan Nurses’ Health Study

Key Points

• Persistent underweight status is a significant risk factor for earlier osteoporosis onset in menopause.
• Women maintaining an underweight body mass index from adolescence show increased osteoporosis risk.
• The findings relate specifically to changes in body mass index over time, emphasizing the importance of early monitoring.
• Understanding these changes could help prevent osteoporosis in women as they age and enter menopause.