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Impact of Alzheimer's co-pathology on basal forebrain atrophy and cognitive decline in Dementia with Lewy Bodies | Synapse
March 3, 2026
Impact of Alzheimer's co-pathology on basal forebrain atrophy and cognitive decline in Dementia with Lewy Bodies
DU
Daniele Urso
University of Bari Aldo Moro
TG
Thomas Giannelli
University of Bari Aldo Moro
BT
Benedetta Tafuri
University of Salento
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Key Points
Cognitive decline is associated with significant basal forebrain atrophy related to Alzheimer's co-pathology.
Participants with dementia with Lewy bodies showed a 30% increase in cognitive decline in patients with Alzheimer's co-pathology.
Observational analysis of patients diagnosed with dementia with Lewy bodies assessed cognitive performance and brain imaging.
Findings highlight the need for further exploration of Alzheimer's effects on dementia with Lewy bodies, emphasizing recovery pathways.
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Cite This Study
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Urso et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75eaec6e9836116a2986e
https://doi.org/https://doi.org/10.1016/j.jns.2025.124651