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March 3, 2026
Treosulfan-Based Conditioning and Sirolimus-Ptcy Gvhd Prophylaxis in Allogeneic Stem Cell Transplantation for Aggressive B-cell NHL
LL
Lorenzo Lazzari
RG
Raffaella Greco
Vita-Salute San Raffaele University
FC
F. Ciceri
Vita-Salute San Raffaele University
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Key Points
Improved outcomes are observed with treosulfan-based conditioning and sirolimus-GVHD prophylaxis.
A significant reduction in GVHD incidence is reported, showing improved patient health after transplantation.
Assessment using patient records highlights the effectiveness of this dual approach in aggressive B-cell NHL.
Further validation is needed, as clinical effectiveness is based on single-institution findings, limiting broader applicability.
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Lazzari et al. (Sun,) studied this question.
synapsesocial.com/papers/69a7607fc6e9836116a2d482
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.546
التكييف القائم على التروسولفان والوقاية من غمد الخلايا T بمساعدة السيrolimus في زراعة الخلايا الجذعية المكونة من متبرع لسرطان الغدد الليمفاوية B العدواني | Synapse