Dynamics of gut bacteriophage in diversity outbred mice studied over lifespan and during extreme caloric restriction | Synapse
March 5, 2026Open Access
Dynamics of gut bacteriophage in diversity outbred mice studied over lifespan and during extreme caloric restriction
Key Points
The research aims to explore the dynamics of gut bacteriophage populations over the lifespan of diversity outbred mice and under extreme caloric restriction.
Longitudinal study design assessing mice over their lifespan
Monitoring gut bacteriophage populations
Application of caloric restriction to observe effects
Highlight the dominance of 'piggyback-the-winner' strategies in phage dynamics
Show variations in bacteriophage diversity linked to lifespan stages
Uncover the impact of caloric restriction on gut microbial balance
Abstract
These studies enrich our understanding of DNA phage dynamics in gut while emphasizing the predominance of "piggyback-the-winner" strategies.