Comparative effectiveness of misoprostol plus letrozole versus misoprostol alone for pharmacological abortion: a systematic review and meta-analysis of randomized controlled trials.

Key Points

• To compare the effectiveness of misoprostol with and without letrozole in pharmacological abortion.
• Conducted a systematic review and meta-analysis of randomized controlled trials
• Compared abortion outcomes between two treatment groups
• Analyzed side effects associated with the treatments
• Letrozole pre-treatment significantly improves the efficacy of misoprostol for abortion
• No increase in side effects was observed with the addition of letrozole