Bullous Systemic Lupus Erythematosus in a Southeast Asian Cohort: High Systemic Association Driving Systemic Therapy.

Key Points

• This research aims to explore the systemic associations and treatment implications of bullous systemic lupus erythematosus (BSLE).
• Review of literature related to bullous systemic lupus erythematosus.
• Analysis of systemic involvement patterns, especially renal and hematologic.
• Assessment of treatment approaches, particularly the use of immunosuppressive agents.
• BSLE is an uncommon manifestation of systemic lupus erythematosus but shows high systemic association.
• Strong links were found between BSLE and renal/hematologic diseases.
• Immunosuppressive agents are often required for effective management.