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This research investigates the effects of prenatal ethanol exposure on brain and behavior in mice across generations.

March 25, 2026

Paternal lineage effects of prenatal ethanol exposure: Offspring neuroanatomy and behavior in a multigenerational mouse model of FASD

This research investigates the effects of prenatal ethanol exposure on brain and behavior in mice across generations.
Used a multigenerational mouse model
Assessed neuroanatomy and behavior of offspring
Evaluated heritable effects of prenatal exposure
Identified abnormal brain development in offspring
Observed behavioral changes linked to prenatal ethanol exposure
Detected transgenerational heritable effects in subsequent generations

Our data suggest that PrEE can result in abnormal brain and behavioral development with heritable effects that persist transgenerationally.

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Conner et al. (Sun,) studied this question.

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Kathleen E. Conner

Roberto F. Perez

Michael A. Erickson

Alcohol Clinical and Experimental Research

University of California, Riverside

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