Does early rhythm-control therapy reduce adverse cardiovascular outcomes in patients with early atrial fibrillation and cardiovascular conditions?
Patients with early atrial fibrillation and cardiovascular conditions
Early rhythm-control therapy
Usual care
Adverse cardiovascular outcomescomposite
Early rhythm-control therapy is associated with improved cardiovascular outcomes compared to usual care in patients with early atrial fibrillation.
Early rhythm-control therapy was associated with a lower risk of adverse cardiovascular outcomes than usual care among patients with early atrial fibrillation and cardiovascular conditions. (Funded by the German Ministry of Education and Research and others; EAST-AFNET 4 ISRCTN number, ISRCTN04708680; ClinicalTrials.gov number, NCT01288352; EudraCT number, 2010-021258-20.).
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Kirchhof et al. (Sat,) studied this question.
www.synapsesocial.com/papers/69c940299e1f3876577a0e03 — DOI: https://doi.org/10.1056/nejmoa2019422
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
Paulus Kirchhof
A. John Camm
Andreas Goette
New England Journal of Medicine
University of Birmingham
University of Groningen
Universitat de Barcelona
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