Does catheter ablation reduce the composite end point of death from any cause or hospitalization for worsening heart failure compared to medical therapy in patients with atrial fibrillation and heart failure?
Patients with atrial fibrillation and heart failure
Catheter ablation
Medical therapy
Composite end point of death from any cause or hospitalization for worsening heart failurecomposite
Catheter ablation significantly reduces the composite of all-cause mortality or heart failure hospitalization compared to medical therapy in patients with atrial fibrillation and heart failure.
Catheter ablation for atrial fibrillation in patients with heart failure was associated with a significantly lower rate of a composite end point of death from any cause or hospitalization for worsening heart failure than was medical therapy. (Funded by Biotronik; CASTLE-AF ClinicalTrials.gov number, NCT00643188 .).
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Nassir Marrouche
Johannes Brachmann
Dietrich Andresen
New England Journal of Medicine
Erasmus MC
Semmelweis University
St. Antonius Ziekenhuis
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Marrouche et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69c940299e1f3876577a0e07 — DOI: https://doi.org/10.1056/nejmoa1707855