What question did this study set out to answer?

This research investigates how patient factors influence adverse outcomes during surgeries in users of GLP-1 receptor agonists.

March 30, 2026Open Access

Are patient factors associated with adverse perioperative outcomes in GLP-1 receptor agonist users? A retrospective cohort study

Key Points

This research investigates how patient factors influence adverse outcomes during surgeries in users of GLP-1 receptor agonists.
Conducted a retrospective cohort analysis of GLP-1RA users
Evaluated patient demographics including gender and ethnicity
Assessed the presence of comorbidities like COPD and asthma
Female and Hispanic GLP-1RA users faced higher perioperative risks
GLP-1RAs were linked to fewer complications in patients with COPD or asthma
Findings suggest a need for tailored perioperative management based on patient characteristics

Abstract

GLP-1RA users generally had more favorable outcomes, but females, Hispanics, and patients with select comorbidities had increased risks. GLP-1RAs may reduce complications in patients with COPD or asthma. Clinical trials in GLP-1RA users should consider differences across comorbidities to optimize perioperative care.

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Cite This Study

Fanizza et al. (Thu,) studied this question.

synapsesocial.com/papers/69ca1280883daed6ee094e97 https://doi.org/https://doi.org/10.1016/j.jclinane.2026.112192

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