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The HL-60 cell line, derived from a single patient with acute promyelocytic leukemia, provides a unique in vitro model system for studying the cellular and molecular events involved in the proliferation and differentiation of normal and leukemic cells of the granulocyte/monocyte/macrophage lineage.
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SJ Collins (Sun,) studied this question.
www.synapsesocial.com/papers/69d721493f906f6a06bef43f — DOI: https://doi.org/10.1182/blood.v70.5.1233.1233
SJ Collins
Blood
Fred Hutch Cancer Center
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa
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