Co-exposure to a high-fat diet and nanoplastics synergistically exacerbates intestinal microbiota dysbiosis and susceptibility

Key Points

• This research aims to understand how combined exposure to a high-fat diet and nanoplastics influences gut health.
• Evaluated the impact of a high-fat diet and nanoplastics on gut microbiota.
• Analyzed changes in microbial composition and diversity.
• Assessed susceptibility to dysbiosis in affected populations.
• Combined exposure resulted in significant dysbiosis compared to individual factors.
• Notable alterations in microbial diversity were observed.
• Increased susceptibility to gut-related health issues was identified.

Abstract