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This work aims to develop a multifunctional liposome that addresses multidrug resistance in breast cancer.

April 10, 2026

Multifunctional ginsenoside Rg3-integrated liposomes for synergistic chemo-photothermal-immunotherapy against multidrug-resistant breast cancer

Key Points

This work aims to develop a multifunctional liposome that addresses multidrug resistance in breast cancer.
Developed liposomes by replacing cholesterol with ginsenoside Rg3.
Incorporated DSPE-PEG2000 for extended circulation time.
Encapsulated therapeutic agents for combined treatment approaches.
Enhanced therapeutic efficacy in overcoming multidrug resistance.
Improved systemic circulation and targeting of cancer cells.
Synergistic effects observed in chemo-photothermal-immunotherapy.

Abstract

To address multidrug resistance (MDR) in breast cancer, a multifunctional liposome (RID-LPs) was developed by replacing cholesterol with ginsenoside Rg3 and incorporating DSPE-PEG2000 for prolonged systemic circulation. This nanoplatform encapsulates...

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Authors

Wuyan Xie

Kai Wang

Qin Zhou

Journals

Journal of Materials Chemistry B

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Multifunctional ginsenoside Rg3-integrated liposomes for synergistic chemo-photothermal-immunotherapy against multidrug-resistant breast cancer

Key Points

Abstract

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Connected Papers

Discussion

Authors

Journals

Actions

References and Citations

Citation Network

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