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These results confirm that IHC or FISH HER2 testing is appropriate for patient selection for adjuvant trastuzumab therapy. Trastuzumab benefit seemed independent of HER2/centromere 17 ratio and chromosome 17 copy number.
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Perez et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69da4fde84371aa676a3d12e — DOI: https://doi.org/10.1200/jco.2009.26.2154
Edith A. Perez
Monica M. Reinholz
David W. Hillman
Journal of Clinical Oncology
Indiana University – Purdue University Indianapolis
Mayo Clinic in Florida
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