Is relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography sensitive and specific for diagnosing cardiac amyloidosis?
Relative apical sparing of longitudinal strain on 2D speckle-tracking echocardiography is an accurate and reproducible marker for diagnosing cardiac amyloidosis.
CA is characterised by regional variations in LS from base to apex. A relative 'apical sparing' pattern of LS is an easily recognisable, accurate and reproducible method of differentiating CA from other causes of LV hypertrophy.
Phelan et al. (Fri,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: