Left ventricular posterior wall thickness independently predicted cardiac light-chain amyloidosis with an area under the curve of 0.798 in heart failure patients with monoclonal gammopathies.
Cohort (n=187)
No
Does left ventricular posterior wall thickness predict light-chain cardiac amyloidosis in hospitalized heart failure patients with monoclonal gammopathies?
Left ventricular posterior wall thickness is an effective predictor for diagnosing light-chain cardiac amyloidosis in hospitalized heart failure patients with monoclonal gammopathies.
Effect estimate: OR 1.71 (95% CI 1.40-2.10)
p-value: p=<0.001
These findings suggest that LVPW thickness effectively predicts CA-AL in hospitalized heart failure patients with monoclonal gammopathies, thereby providing valuable insights into the diagnostic process for CA-AL.
Yu et al. (Thu,) conducted a cohort in Heart failure with monoclonal gammopathies (n=187). Left ventricular posterior wall (LVPW) thickness vs. Difference in serum free light-chain (dFLC) levels was evaluated on Diagnosis of cardiac light-chain amyloidosis (CA-AL) (OR 1.71, 95% CI 1.40-2.10, p=<0.001). Left ventricular posterior wall thickness independently predicted cardiac light-chain amyloidosis with an area under the curve of 0.798 in heart failure patients with monoclonal gammopathies.