Unveiling the Role of Irisin as a Biomarker in Adolescent and Young Adult PCOS : A Metabolic and Hormonal Comparison of Hyperandrogenic and Normoandrogenic Phenotypes

Key Points

• The aim is to explore the role of irisin as a biomarker in assessing metabolic differences between hyperandrogenic and normoandrogenic PCOS phenotypes.
• Comparison of metabolic and hormonal profiles between HA-PCOS and normoandrogenic PCOS.
• Assessment of irisin levels in adolescents and young adults with PCOS.
• Evaluation of long-term complications associated with metabolic disruption.
• HA-PCOS is associated with more significant metabolic disruptions than normoandrogenic PCOS.
• Irisin levels may indicate severity of metabolic issues in HA-PCOS.
• Irisin could help in predicting long-term health complications related to PCOS.

Abstract