The developed colorimetric LAMP assay provides a simple, fast, and reliable alternative to polymerase chain reaction-based methods for screening hemoglobinopathies involving large deletions. Its visual detection and minimal equipment requirements make it suitable for low-resource or point-of-care settings. Further validation with larger cohorts and additional variants is recommended to enhance the assay's clinical utility.
Riahi et al. (Sat,) studied this question.