External ligand-free Pd-catalyzed 1,4-hydrosilylation of pyridines: mechanistic implication of dearomative remote hydride shift

Key Points

• The Pd catalytic system achieves regioselective hydrosilylation, ensuring high yield and broader substrate compatibility.
• Pyridines and quinolines are effectively transformed through a ligand-free method, showcasing versatility in functional groups.
• The mechanistic insights highlight the significance of dearomative remote hydride shifts for the observed selectivity.
• This approach underscores the importance of simplicity in catalytic design for complex organic transformations.

Abstract