What is the impact of whole-blood donation frequency on donor health? A systematic review.

Key Points

• The research aims to evaluate how the frequency of whole-blood donation affects donor health.
• Conducted a systematic review of current evidence on blood donation frequency and health outcomes.
• Analyzed adherence to WHO guidelines regarding inter-donation intervals for men and women.
• Considered existing studies and recommendations for safe blood donation practices.
• Current WHO guidelines suggest a minimum of 12 weeks between donations for men and 16 weeks for women.
• Recommendations are made due to a lack of robust evidence from high-quality randomized controlled trials (RCTs).
• Further research is necessary to determine the long-term health effects of donation frequency.