A new lipase-based purification method enables large-scale production of high-quality Rhinovirus C preparations to support structural studies and therapeutic development.
We present a robust system for large-scale RV-C15a production in adherent HeLa-E8 cells and recommend a lipase-based purification method as a rapid and effective approach for producing high-quality viral preparations. These advances will support structural studies and accelerate the development of RV-C-targeted therapeutics and vaccines.
Kaiya et al. (Wed,) studied this question.