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March 3, 2026
Pro-Tumorigenic Roles of Cyclin Dependent Kinase 2 and its Associated Cyclins in Cholangiocarcinoma Progression under High Glucose Condition
CT
Cheerapinya Taebprakhon
Khon Kaen University
SS
Supannika Sorin
Khon Kaen University
KK
Kullanat Khawkhiaw
Khon Kaen University
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Key Points
Cholangiocarcinoma progression correlates with cyclin dependent kinase 2 activity under high glucose.
High glucose condition promotes tumor growth, highlighting a new metabolic perspective on treatment.
Analysis of cellular mechanisms reveals interactions between cyclin dependent kinase 2 and cyclins.
These findings may lead to targeted therapies focusing on glucose metabolism in cholangiocarcinoma.
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Taebprakhon et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75eaec6e9836116a2986b
https://doi.org/https://doi.org/10.1016/j.arcmed.2026.103383
Pro-Tumorigenic Roles of Cyclin Dependent Kinase 2 and its Associated Cyclins in Cholangiocarcinoma Progression under High Glucose Condition | Synapse