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Rotavirus induces mucosal B-cell responses through the TLR3/TRIF and MAVS pathways | Synapse
March 3, 2026
Rotavirus induces mucosal B-cell responses through the TLR3/TRIF and MAVS pathways
RZ
Rongrong Zhang
Jilin Agricultural University
YY
Y. H. Yang
Central South University
MW
M. WANG
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Key Points
Mucosal b-cell responses are significantly upregulated following rotavirus infection, indicating immune activation.
The study identifies key pathways, TLR3/TRIF and MAVS, involved in the immune response related to rotavirus.
Analysis utilized in vitro models to assess the specific roles of TLR3 and MAVS pathways in B-cell activation.
Understanding these pathways may enable the development of targeted vaccines or treatments against rotavirus.
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Zhang et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75ef6c6e9836116a29ff2
https://doi.org/https://doi.org/10.1016/j.vetmic.2026.110910