Epidemiology of CADASIL and the spectrum of its neurologic and systemic manifestations: A nationwide study in Korea

Key Points

• CADASIL shows a diverse range of neurologic and systemic manifestations in affected individuals, indicating its varied clinical presentation.
• Among the studied population, the prevalence of CADASIL-related neurologic symptoms was found to be significant, impacting daily activities and quality of life.
• Analysis of nationwide health records was conducted to identify and characterize the manifestations associated with CADASIL across diverse demographics.
• These findings underscore the need for comprehensive management strategies to address the broad spectrum of symptoms associated with CADASIL.