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The ALS copycat: Unmasking an inflammatory myopathy disguised as motor neuron disease | Synapse
March 3, 2026
The ALS copycat: Unmasking an inflammatory myopathy disguised as motor neuron disease
AP
Abigail Carpio Peña
WA
Wolfgang Trillo Alvarez
Catholic University of Santa María
KP
Karol Choque Pereyra
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Key Points
Inflammatory myopathy can mimic symptoms of motor neuron disease, complicating diagnoses for clinicians.
Key biomarkers identified include elevated immune response indicators, aiding in clinical distinctions.
Observational analysis of patient records reveals cases where misdiagnosis occurred, increasing treatment delays.
This unmasking may enable more accurate diagnoses and timely intervention for patients experiencing similar symptoms.
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Cite This Study
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Peña et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75f74c6e9836116a2ad5d
https://doi.org/https://doi.org/10.1016/j.jns.2025.124275