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Cause-Specific Mortality in Multiple Myeloma Pre- and Post-CAR-T cell Therapy Approval | Synapse
March 3, 2026
Cause-Specific Mortality in Multiple Myeloma Pre- and Post-CAR-T cell Therapy Approval
KE
Khaled Elhusseiny
East Carolina University
MC
Mahija Cheekati
Ochsner Medical Center
AM
Alaa Eldin Mahmoud Mahmoud
Key Points
Mortality rates for multiple myeloma significantly decreased after CAR-T cell therapy approval, indicating better patient outcomes.
Survival analysis found a reduction in cause-specific mortality during the period following CAR-T adoption, showing a clear trend.
Observational analysis of patient records from various health systems highlights the impact of newer treatment options.
These findings may support future healthcare decisions and signify the potential of CAR-T therapies in improving survival.
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Elhusseiny et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760afc6e9836116a2dae2
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.635