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Lycorine improves inflammatory imbalance in diabetic cardiomyopathy by targeting ILF3 | Synapse
March 3, 2026
Lycorine improves inflammatory imbalance in diabetic cardiomyopathy by targeting ILF3
QZ
Qian Zhou
XJ
Xuejin Jin
MY
Miao Yuan
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Key Points
Lycorine significantly reduces inflammatory imbalance in diabetic cardiomyopathy, showing promise as a therapeutic agent.
Cytokine levels decreased by 40% with lycorine treatment in mouse models, indicating its efficacy in targeting inflammation.
Assessment using molecular pathways demonstrates that lycorine effectively interacts with ILF3 to mediate inflammatory responses.
Highlights the need for further studies on lycorine's effects, as results are based on preclinical models with implications for human treatment.
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Zhou et al. (Sat,) studied this question.
synapsesocial.com/papers/69a76115c6e9836116a2ea8b
https://doi.org/https://doi.org/10.1016/j.phymed.2026.157976
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