Within-host invasion dynamics of SARS-CoV-2 through membrane fusion and endocytosis: A case study of a patient from a German hospital

Key Points

• SARS-CoV-2 employs membrane fusion and endocytosis to invade host cells, demonstrating significant dynamics.
• Key evidence shows that this dual mechanism is crucial for effective viral proliferation within the host environment.
• Analysis focused on the within-host dynamics of the viral invasion mechanisms in a clinical case, revealing intricate details of infection processes.
• Understanding these mechanisms could highlight new targets for therapeutic intervention against COVID-19, emphasizing the importance of further research.