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Tunable 2H-azirines for kinetically favored reactions with geminal dicarboxylic acids | Synapse
March 3, 2026
Tunable 2H-azirines for kinetically favored reactions with geminal dicarboxylic acids
VN
Victoria Nisoli
California Institute of Technology
DS
Dulanjali S. Sooriyage
AO
Atul Ojha
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Key Points
The results indicate that tunable 2H-azirines significantly improve kinetic favorability in specific reactions.
Key evidence shows enhanced reaction rates with geminal dicarboxylic acids under defined conditions.
Assessment of kinetic pathways reveals new synthetic strategies in organic chemistry involving 2H-azirines.
Implications suggest expanded use of 2H-azirines, though practical applications may require further validation.
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Nisoli et al. (Wed,) studied this question.
synapsesocial.com/papers/69a761b2c6e9836116a2fc02
https://doi.org/https://doi.org/10.1016/j.tetlet.2026.156009
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