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March 3, 2026
Open Access
Psilocybin-assisted therapy for relapse prevention in alcohol use disorder: a phase 2 randomized clinical trial
NR
Nathalie M. Rieser
Johns Hopkins University
RB
Raoul Bitar
University of Zurich
SH
Simon Halm
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Key Points
Psilocybin-assisted therapy significantly reduces relapse rates in alcohol use disorder patients, potentially aiding recovery.
Patients receiving psilocybin therapy showed a 50% reduction in relapse within 6 months compared to the control group.
Conducted as a phase 2 randomized clinical trial, this research supports the therapeutic use of psilocybin for addiction treatment.
Findings may enable broader applications of psilocybin in interventions for various substance use disorders.
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Rieser et al. (Tue,) studied this question.
synapsesocial.com/papers/69a765c6badf0bb9e87da643
https://doi.org/https://doi.org/10.5167/uzh-284304
Psilocybin-assisted therapy for relapse prevention in alcohol use disorder: a phase 2 randomized clinical trial | Synapse