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Bone marrow mesenchymal stem cells ameliorate intermittent multiple sclerosis: quantitative cerebellar microscopy and functional analysis in cuprizone-induced mice | Synapse
March 3, 2026
Bone marrow mesenchymal stem cells ameliorate intermittent multiple sclerosis: quantitative cerebellar microscopy and functional analysis in cuprizone-induced mice
MH
Maedeh Hashemi
IK
Iraj Ragerdi Kashani
Tehran University of Medical Sciences
PP
Parichehr Pasbakhsh
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Key Points
Bone marrow mesenchymal stem cells significantly improve outcomes in multiple sclerosis models, enhancing overall function.
Quantitative assessment shows notable changes in cerebellar structure and function with stem cell treatment.
Assessment using quantitative cerebellar microscopy revealed profound structural improvements post-intervention.
Highlights potential for future therapies in multiple sclerosis, though results were obtained from mouse models; further studies are needed.
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Hashemi et al. (Fri,) studied this question.
synapsesocial.com/papers/69a767e4badf0bb9e87e2c97
https://doi.org/https://doi.org/10.1007/s10072-025-08799-z