Immunohistochemical detection of PD-L1 in small cell lung cancer and its prognostic values

Key Points

• PD-L1 expression significantly predicts poor survival outcomes in small cell lung cancer patients.
• Immunohistochemistry shows higher sensitivity for detecting PD-L1 compared to RT-qPCR methods.
• Aggressive clinicopathological features are associated with increased PD-L1 expression in small cell lung cancer.
• The findings highlight the importance of PD-L1 as a potential biomarker for treatment decisions.