Association of Interictal Respiratory Variability and Severity of Postictal Hypoxemia After Generalized Convulsive Seizures

Key Points

• Assess the relationship between interictal respiratory variability and postictal hypoxemia severity following generalized convulsive seizures (GCS).
• Utilized measures of interictal respiratory variability
• Evaluated hypoxemia severity after GCS
• Analyzed data from individuals with epilepsy (PWE)
• Increased interictal respiratory variability correlates with prolonged hypoxemia post-GCS.
• Higher variability may indicate baseline respiratory dysregulation in some PWE.
• Findings suggest that respiratory variability could serve as a potential surrogate for SUDEP risk.