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GSK3 regulates DOG1L4 to enhance pre‐harvest sprouting resistance in wheat | Synapse

March 18, 2026

GSK3 regulates DOG1L4 to enhance pre‐harvest sprouting resistance in wheat

Key Points

Investigate the role of GSK3 in regulating DOG1L4 and its impact on seed dormancy in wheat.
Explored the phosphorylation of DOG1L4 and ABI5 by GSK3
Analyzed the interaction between GSK3 and dormancy proteins in wheat seeds
Examined the effects on germination and dormancy control.
GSK3 phosphorylates and stabilizes DOG1L4
Enhanced ABI5 activation was observed
Increased seed dormancy was linked to GSK3 activity.

Abstract

GLYCOGEN SYNTHASE KINASE 3 (GSK3), a negative regulator of brassinosteroid signaling, phosphorylates and stabilizes the seed dormancy protein DOG1L4, which in turn activates ABSCISIC ACID INSENSITIVE 5 (ABI5) to enhance seed dormancy. GSK3 also phosphorylates ABI5. This dual-target mechanism suggests a strategy for controlling seed dormancy and germination in crops.

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Cite This Study

Dong et al. (Sun,) studied this question.

synapsesocial.com/papers/69ba427c4e9516ffd37a2d71 https://doi.org/https://doi.org/10.1111/jipb.70234