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SCANPY is a scalable toolkit for analyzing single-cell gene expression data. It includes methods for preprocessing, visualization, clustering, pseudotime and trajectory inference, differential expression testing, and simulation of gene regulatory networks. Its Python-based implementation efficiently deals with data sets of more than one million cells ( https://github.com/theislab/Scanpy ). Along with SCANPY, we present ANNDATA, a generic class for handling annotated data matrices ( https://github.com/theislab/anndata ).
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Wolf et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69c26b53c51f87703be84226 — DOI: https://doi.org/10.1186/s13059-017-1382-0
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
F. Alexander Wolf
Philipp Angerer
Fabian J. Theis
SHILAP Revista de lepidopterología
Genome biology
Technical University of Munich
Helmholtz Zentrum München
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