Cu² ⁺-Activated NIR Photothermal Conversion Based on Imine Bond Photorotation for Dual-Mode Antibacterial Applications

Key Points

• The study aims to develop a therapeutic system that utilizes Cu²⁺ for enhanced antibacterial activity through NIR photothermal conversion.
• Developed a system that integrates organic molecules with NIR photothermal properties and Cu²⁺ coordination.
• Investigated the antibacterial effects using various concentrations of Cu²⁺ and light exposure.
• Analyzed the efficacy of the system against bacterial strains in vitro.
• The integrated system shows significant antibacterial activity under NIR light exposure.
• Cu²⁺ coordination enhances photothermal conversion efficiency leading to improved therapeutic outcomes.
• In vitro tests reveal a substantial reduction in bacterial viability with combined photothermal and Cu²⁺ effects.