Paternal lineage effects of prenatal ethanol exposure: Offspring neuroanatomy and behavior in a multigenerational mouse model of FASD

Key Points

• This research investigates the effects of prenatal ethanol exposure on brain and behavior in mice across generations.
• Used a multigenerational mouse model
• Assessed neuroanatomy and behavior of offspring
• Evaluated heritable effects of prenatal exposure
• Identified abnormal brain development in offspring
• Observed behavioral changes linked to prenatal ethanol exposure
• Detected transgenerational heritable effects in subsequent generations

Abstract