The role of HCMV proteins in cancer : oncogenesis, oncomodulation, or both?

Key Points

• The aim is to explore the dual roles of HCMV proteins in cancer development and tumor modulation.
• Literature review on HCMV and cancer interactions
• Analysis of viral and cellular pathways
• Assessment of experimental data on HCMV effects in cancer models
• HCMV proteins can promote cancer development through oncogenic pathways.
• These proteins may also influence tumor microenvironment and immune modulation.
• Findings highlight a complex interplay between HCMV infection and cancer progression.