The integration of DNAzyme and droplet-based microfluidics is advancing pathogen detection toward higher sensitivity and throughput. However, this interdisciplinary convergence still faces multiple technical challenges. Based on practical applications, this article systematically outlines current key bottlenecks. It also proposes corresponding strategies and envisions future pathways for intelligent and precision-oriented integration.
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Lei Guan
Shuai Li
Jingyuan Zhao
Analytical Chemistry
Dalian University of Technology
Dalian Medical University
First Affiliated Hospital of Dalian Medical University
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Guan et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69d893406c1944d70ce04375 — DOI: https://doi.org/10.1021/acs.analchem.5c07936