Tumor Lysis Syndrome in Lung Cancer Patients: A Review of the Literature

Key Points

• The central aim is to explore effective management strategies for tumor lysis syndrome in high-risk lung cancer patients.
• Review of existing literature on tumor lysis syndrome and management in lung cancer patients.
• Evaluation of urate-lowering therapy and hydration protocols for preventing TLS.
• Consideration of the role of rasburicase in treating TLS.
• Proactive therapy and hydration may significantly reduce mortality in high-risk lung cancer patients experiencing TLS.
• Multicenter studies could lead to refined diagnostic criteria and guidelines for risk assessment.
• Improved prophylactic measures may benefit other patients with solid tumors.

Abstract