Mechanochemical multicomponent Ugi-azide/post-transformation strategies. Toward more sustainable one-pot diversity-oriented synthesis of complex nitrogen heterocycles.

Key Points

• To develop rapid and efficient mechanochemical processes for synthesizing nitrogen heterocycles.
• Utilized one-pot mechanochemical techniques
• Applied multicomponent strategies
• Synthesized 1,5-disubstituted tetrazoles and analogs
• Achieved synthesis of 1,5-disubstituted tetrazoles
• Created complex bis-heterocycles and polyheterocycles
• Demonstrated versatile and efficient synthetic methods

Abstract