What question did this study set out to answer?

To investigate how post-weaning milk supplementation affects gut microbiome and barrier integrity.

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April 10, 2026Open Access

The JNK2-microbiome axis modulates gut barrier integrity through microbial acetate

Key Points

To investigate how post-weaning milk supplementation affects gut microbiome and barrier integrity.
Utilized immediate post-weaning milk supplementation
Monitored gut microbiome composition
Assessed gut barrier integrity through various metrics
Milk supplementation preserved a beneficial gut microbiome, notably D. newyorkensis
Gut barrier integrity was enhanced with supplementation
A one-week delay in supplementation eliminated the protective effects

Abstract

Our findings show that immediate post-weaning milk supplementation preserves a beneficial gut microbiome, marked by the persistence of D. newyorkensis and enhanced gut barrier integrity. Even a one-week delay eliminates this protective effect, emphasizing the critical timing of post-weaning nutritional intervention for maintaining intestinal health.

The JNK2-microbiome axis modulates gut barrier integrity through microbial acetate

Key Points

Abstract

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