What question did this study set out to answer?

To investigate how general anesthesia influences the neurophysiologic correlates of ketamine.

April 10, 2026

General Anesthesia and Discrete Components of Ketamine Neurophysiology

Key Points

To investigate how general anesthesia influences the neurophysiologic correlates of ketamine.
Cohort study design
Coadministration of ketamine with general anesthesia
Assessment of neurophysiologic correlates including θ and βγ waves
Coadministration selectively modulated θ neurophysiologic correlates of ketamine
No significant modulation of βγ neurophysiologic correlates was observed

Abstract

In this cohort study, coadministration of ketamine with GA selectively modulated the θ but not the βγ neurophysiologic correlates of ketamine. These findings suggest a potential method to explore the role of these components in the behavioral effects of ketamine.

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Discussion

Authors

Ben Deverett

Duan Li

Theresa R. Lii

Journals

JAMA Psychiatry

Actions

Institutions

Stanford University

University of Michigan

University of Auckland

References and Citations

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Building similarity graph...

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General Anesthesia and Discrete Components of Ketamine Neurophysiology

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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