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ESTREL-Fatigue-association of levodopa with post-stroke fatigue. | Synapse

April 10, 2026

ESTREL-Fatigue-association of levodopa with post-stroke fatigue.

Key Points

To evaluate the association of levodopa treatment with post-stroke fatigue during rehabilitation.
Conducted the ESTREL-Fatigue study comparing levodopa with placebo
Assessed post-stroke fatigue levels during in-hospital rehabilitation
Levodopa did not show an association with reduced post-stroke fatigue compared to placebo
No significant differences in fatigue levels were observed between groups

Abstract

In ESTREL-Fatigue, levodopa, compared to placebo, was not associated with less PSF during in-hospital rehabilitation.

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Cite this study

Boos et al. (Sun,) studied this question.

www.synapsesocial.com/papers/69d8962d6c1944d70ce0763f — DOI: https://doi.org/10.1093/esj/aakag029

Authors

L

Lukas Boos

J

Josefin E. Kaufmann

M

Mirjam I Sauter

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Institutions

Harvard University

Stanford University

University of Oxford

References and Citations

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