October 15, 2004

Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate

Key Points

Key points are not available for this paper at this time.

Abstract

By decreasing drug loading per antibody, the therapeutic index was increased demonstrating that drug loading is a key design parameter for antibody-drug conjugates.

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Cite this study

Hamblett et al. (Fri,) studied this question.

www.synapsesocial.com/papers/69d964848988aeabbe685211 — DOI: https://doi.org/10.1158/1078-0432.ccr-04-0789

Authors

Kevin J. Hamblett

Peter D. Senter

Dana F. Chace

Journals

Clinical Cancer Research

Actions

Institutions

Seagen (United States)

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion