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Neuropsychological function can be assessed by telephone in a multicenter trial. Long-term neuropsychological impairment is common in survivors of ALI. Hypoxemia is a risk factor for long-term neuropsychological impairment. Fluid management strategy is a potential risk factor for long-term cognitive impairment; however, given the select population studied and an unclear mechanism, this finding requires confirmation.
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Mark E. Mikkelsen
Jason D. Christie
Paul N. Lanken
American Journal of Respiratory and Critical Care Medicine
University of Pennsylvania
Massachusetts General Hospital
University of Pittsburgh
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Mikkelsen et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69dd60b10a7b4bc8c4101d93 — DOI: https://doi.org/10.1164/rccm.201111-2025oc
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