As ventricular entry becomes increasingly common during supramaximal glioblastoma resection, our data demonstrate that patients who develop postoperative hydrocephalus have more readmissions, longer hospital stays, and worse functional status. Thus, strategies to reduce postoperative hydrocephalus are critical. Although it does not alter the natural course of glioblastoma itself, we find that CPC represents a safe and effective adjunct that prevents postoperative hydrocephalus, reduces hospital readmissions, and downstream interventions, which is extremely important to a patient cohort with limited expected survival.
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Stuart D Harper
Amani Carson
Jacob Alderete
Neurosurgery
University of California, Los Angeles
Neurobehavioral Systems
Samueli Institute
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Harper et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69df2b04e4eeef8a2a6afffc — DOI: https://doi.org/10.1227/neu.0000000000004036