Evaluating the impact of medication review and deprescribing on prescribing appropriateness and clinical outcomes in older people residing in long-term care facilities: a systematic review and meta-analysis

Key Points

• To assess the effectiveness of medication review and deprescribing interventions on prescribing appropriateness and clinical outcomes in older residents of long-term care facilities.
• Conducted a systematic review and meta-analysis of relevant studies.
• Focused on older adults living in long-term care facilities (LTCF) with polypharmacy.
• Evaluated the impact on prescribing appropriateness and clinical outcomes, including falls and hospitalisations.
• Medication review interventions improved prescribing appropriateness in older LTCF residents.
• No significant impact on clinical outcomes like falls, hospitalizations, and mortality was found.

Abstract